該研究的通訊作者為清華大學(xué)藥學(xué)院杜娟娟副教授，第一作者為清華大學(xué)藥學(xué)院博士生張亞寧（PTN項(xiàng)目）、丁燕超和曾子顏。清華大學(xué)X射線晶體平臺(tái)和藥學(xué)技術(shù)中心、顏寧教授、肖百龍教授及北京大學(xué)黃卓教授為該研究提供了極大幫助。該研究得到了國(guó)家自然科學(xué)基金（82373774）、清華大學(xué)主動(dòng)科學(xué)研究計(jì)劃、北京結(jié)構(gòu)生物學(xué)高等創(chuàng)新中心和清華-北京生命科學(xué)聯(lián)合中心（CLS）項(xiàng)目的資助。

1. Santos, R., Ursu, O., Gaulton, A., Bento, A.P., Donadi, R.S., Bologa, C.G., Karlsson, A., Al-Lazikani, B., Hersey, A., Oprea, T.I., and Overington, J.P. (2017). A comprehensive map of molecular drug targets. Nat. Rev. Drug Discov. 16, 19-34. 10.1038/nrd.2016.230.

2. Wulff, H., Christophersen, P., Colussi, P., Chandy, K.G., and Yarov-Yarovoy, V. (2019). Antibodies and venom peptides: new modalities for ion channels. Nat Rev Drug Discov 18, 339-357. 10.1038/s41573-019-0013-8.

3. Koivisto, A.P., Belvisi, M.G., Gaudet, R., and Szallasi, A. (2022). Advances in TRP channel drug discovery: from target validation to clinical studies. Nature Reviews Drug Discovery 21, 41-59. 10.1038/s41573-021-00268-4.

4. Zhang, M., Ma, Y.M., Ye, X.L., Zhang, N., Pan, L., and Wang, B. (2023). TRP (transient receptor potential) ion channel family: structures, biological functions and therapeutic interventions for diseases. Signal Transduct Tar 8. ARTN 261